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Reproducibility of academic preclinical translational research: lessons  from the development of Hedgehog pathway inhibitors to treat cancer | Open  Biology
Reproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancer | Open Biology

Reproducibility of academic preclinical translational research: lessons  from the development of Hedgehog pathway inhibitors to treat cancer | Open  Biology
Reproducibility of academic preclinical translational research: lessons from the development of Hedgehog pathway inhibitors to treat cancer | Open Biology

Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression  and Inhibits Proliferation of Canine Osteosarcoma Cells
Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells

The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of  Prostate Cancer Cells
The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells

Sonidegib - an overview | ScienceDirect Topics
Sonidegib - an overview | ScienceDirect Topics

The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of  Prostate Cancer Cells
The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells

GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide  treatment | Journal of Experimental & Clinical Cancer Research | Full Text
GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment | Journal of Experimental & Clinical Cancer Research | Full Text

Chemical, computational and functional insights into the chemical stability  of the Hedgehog pathway inhibitor GANT61
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via  JNK-dependent but p53-independent mechanism - ScienceDirect
RITA downregulates Hedgehog-GLI in medulloblastoma and rhabdomyosarcoma via JNK-dependent but p53-independent mechanism - ScienceDirect

Scheme 1. Synthetic pathway to obtain both GANT61-D and GANT61. | Download  Scientific Diagram
Scheme 1. Synthetic pathway to obtain both GANT61-D and GANT61. | Download Scientific Diagram

Chemical, computational and functional insights into the chemical stability  of the Hedgehog pathway inhibitor GANT61
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

Targeting the hedgehog signal transduction pathway at the level of GLI  inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013  - International Journal of Cancer - Wiley Online Library
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013 - International Journal of Cancer - Wiley Online Library

Targeting the hedgehog signal transduction pathway at the level of GLI  inhibits neuroblastoma cell growth <i>in vitro</
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro

Effect of GANT61 and IR in vivo. (A) Relative tumor growth of 22Rv1... |  Download Scientific Diagram
Effect of GANT61 and IR in vivo. (A) Relative tumor growth of 22Rv1... | Download Scientific Diagram

Chemical, computational and functional insights into the chemical stability  of the Hedgehog pathway inhibitor GANT61
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

GANT61 inhibits the expression of GLI1, GLI2 and Bcl-2. a GANT61... |  Download Scientific Diagram
GANT61 inhibits the expression of GLI1, GLI2 and Bcl-2. a GANT61... | Download Scientific Diagram

Canonical and noncanonical Hedgehog/GLI signaling in hematological  malignancies. | Semantic Scholar
Canonical and noncanonical Hedgehog/GLI signaling in hematological malignancies. | Semantic Scholar

Inhibition of GLI-mediated transcription and tumor cell growth by  small-molecule antagonists | PNAS
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists | PNAS

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine  derivatives inhibits melanoma cell growth by inducing replication stress  and mitotic catastrophe | Cell Death & Disease
Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe | Cell Death & Disease

The HH signaling inhibitor GANT61 has an impact on HH target gene... |  Download Scientific Diagram
The HH signaling inhibitor GANT61 has an impact on HH target gene... | Download Scientific Diagram

The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of  Prostate Cancer Cells
The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells

Targeting the hedgehog signal transduction pathway at the level of GLI  inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013  - International Journal of Cancer - Wiley Online Library
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo - Wickström - 2013 - International Journal of Cancer - Wiley Online Library

GANT-61 treatment to RMS cells inhibits proliferation, colony formation...  | Download Scientific Diagram
GANT-61 treatment to RMS cells inhibits proliferation, colony formation... | Download Scientific Diagram

Cells | Free Full-Text | Recent Advances in the Clinical Targeting of  Hedgehog/GLI Signaling in Cancer | HTML
Cells | Free Full-Text | Recent Advances in the Clinical Targeting of Hedgehog/GLI Signaling in Cancer | HTML